Opioid dependence is a chronic, relapsing disease that can be fatal if untreated. Engaging patients in research regarding their perceptions of treatment provides a comprehensive assessment of treatment needs and barriers. Treatment with injectable DAM (or HDM) is preferred by participants and considered effective in reducing the burden of opioid dependency. Participants receiving MMT described disappointment with being randomized to this treatment however, positive aspects, including the quick titration time and availability of auxiliary services, were also discussed.
Females discussed the adjustment required for the clinical setting, while males focused on the challenging clinic schedule and its impact on employment abilities. Participants receiving injectable medications suggested that the supervised delivery model was stringent but provided valuable stability to their lives. A thematic analysis was used over successive phases and was driven by the semantic meanings of the data. Semi-structured interviews were audio-recorded and transcribed verbatim. A phenomenological theoretical framework was used.
MethodsĪ qualitative sub-study was conducted with 29 participants (12 female): 18 (62.1%) received injectable DAM or HDM and 11 (37.9%) received MMT. This study aimed to determine participants’ perceptions of treatment delivered in NAOMI.
Free clinical trials to stop opiates trial#
The North American Opiate Medication Initiative (NAOMI) clinical trial compared the effectiveness of injectable diacetylmorphine (DAM) or hydromorphone (HDM) to oral methadone maintenance treatment (MMT).